Case Studies
Neuroreader® has been independently validated in peer-reviewed research and clinical practice as a reliable, FDA-cleared tool for fast and accurate brain volumetric analysis. Dr. Cyrus A. Raji demonstrates how to interpret Neuroreader® Reports in the following clinical case studies:
Case Study: Using Neuroreader® Volumetric MRI to Diagnose Alzheimer’s Dementia
A 78-year-old woman presented with progressive memory loss. To support clinical evaluation, her physician ordered a 3D T1 volumetric MRI sequence, which was analyzed using Neuroreader®, an advanced software for automated brain volumetry. The Neuroreader® Report provided objective, quantitative insights into her brain structure volumes, helping guide a more accurate diagnosis of Alzheimer’s dementia.
Case Study: Longitudinal MRI Volumetry in Alzheimer’s Disease and Traumatic Brain Injury
A 69-year-old woman with memory loss and depression underwent four MRI scans over seven years (ages 62, 64, 66, and 69). Using Neuroreader® volumetric software, progressive changes were quantified and tracked across key brain regions.
Frontal Temporal Dementia
This video presents a real-world Neuroreader® case review designed for clinicians and imaging specialists. Through guided interpretation and expert commentary, viewers gain hands-on insight into using brain volumetrics for early detection, differential diagnosis, and tracking neurological disorder progression. The session emphasizes how quantitative brain measurements improve diagnostic confidence and enhance patient management.
Applying Quantitative Neuroimaging With Neuroreader® in Geriatric Psychiatry
By Cyrus A. Raji, MD, PhD, and David A. Merrill, MD, PhD
Published in Today’s Geriatric Medicine, Vol. 9, No. 5, p.16.
Alzheimer’s disease (AD) is the leading cause of dementia, currently affecting over 5 million Americans, with cases expected to rise dramatically as the population ages. While AD is incurable, other conditions such as late-life depression, vascular dementia, and traumatic brain injury can mimic its symptoms, often leading to misdiagnosis and delayed treatment.
About Dr. Cyrus A. Raji
Cyrus A. Raji, MD, PhD is a diagnostic neuroradiologist at Barnes Hospital, Washington University in St. Louis, Missouri, with internationally recognized expertise in neuroimaging. His research and clinical work focus on applying multi-modal structural and functional imaging to neuropsychiatric disorders and head trauma.
Credentials & Achievements
- Diagnostic Radiology Residency, UCLA Medical Center (4 years)
- 2016 Radiological Society of North America (RSNA) Roentgen Research Award for outstanding contributions in Radiologic Research
- Fellowship in Traumatic Brain Injury (TBI), UCSF San Francisco (2 years)
- 2017 American Society of Neuroradiology Boeger Award Grant for Alzheimer’s Imaging research
- Published 30+ peer-reviewed papers in leading journals including Neurology, Human Brain Mapping, American Journal of Preventive Medicine, and American Journal of Neuroradiology
Do you want to know more about our software?
Fill out the form below and we will get back to you as soon as possible.